Influenza vaccines containing hemagglutinin and matrix proteins

摘要

Disclosed is a purified surface antigen or split virion influenza vaccine comprising influenza virus haemagglutinin and a fragment of M1 matrix protein which co-purify, wherein said matrix protein fragment comprises a T cell epitope of said M1 matrix protein and has a molecular weight that is less than or equal to 10kDa, and wherein the composition does not contain ovalbumin.