发明名称 ANTIVIRAL NUCLEOSIDE ANALOGS
摘要 Disclosed is the use of a compound of formula (I) in the manufacture of a medicament for treating viral infections where in the substituents are as disclosed in the specification and examples of compounds of formula (I) are: (2S,3R,4R,5R)-2-(4-Aminopyrrolo[1,2-j][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol; (2S,3R,4R,5R)-2-(4-(Dimethylamino)pyrrolo[1,2-j][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol; and (2S,3R,4R,5R)-2-(4-Amino-5-bromopyrrolo[1,2-j][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol. Examples of the viral infection are from the group consisting of: hepatitis B, hepatitis C, human immunodeficiency virus, Polio, Coxsackie A and B, Rhino, Echo, small pox, Ebola, and West Nile virus.
申请公布号 NZ578556(A) 申请公布日期 2012.04.27
申请号 NZ20080578556 申请日期 2008.01.11
申请人 BIOCRYST PHARMACEUTICALS, INC. 发明人 BABU, YARLAGADDA S;CHAND, POORAN;KUMAR, V
分类号 C07H19/23;A61K31/706;A61P31/12;A61P35/00 主分类号 C07H19/23
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