发明名称 INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE
摘要 Disclosed is a poly(ADP-ribose)polymerase compound of formula (Ik), wherein the substituents are as defined within the specification. An example of a compound of formula (Ik) includes 1-(2-fluoro-5-((4-oxo-3,4,5,6,7,8-hexahydrophthalazin-1-yl)methyl)phenyl)pyrrolidine-2,5-dione. Further disclosed is a pharmaceutical composition comprising a compound of formula (Ik), and the use of a compound of formula (Ik) for treating cancer and reducing tumour volume.
申请公布号 NZ577348(A) 申请公布日期 2012.04.27
申请号 NZ20070577348 申请日期 2007.12.20
申请人 ABBOTT LABORATORIES 发明人 GANDHI, VIRAJ B;GIRANDA, VINCENT L;GONG, JIANCHUN;PENNING, THOMAS D;ZHU, GUI-DONG
分类号 A01N43/58;A61K31/495;A61K31/50;C07D237/32;C07D403/10 主分类号 A01N43/58
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