发明名称 SALTS OF PYRROLOPYRIMIDINONE DERIVATIVES AND METHOD OF OBTAINING THEM
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention relates to novel acid-additive salts of pyrrolopyrimidinone derivative, represented by formula (1) which is selected from gentisate, maleate, citrate, fumarate and semitartrate salts, which possess improved properties in their application, in particular higher stability. ^ EFFECT: invention also relates to method of obtaining acid-additive salts of pyrrolopyrimidinone derivative, represented by formula (1) and to pharmaceutical composition, containing them, for treatment and prevention of erectile dysfunction, pulmonary arterial hypertension, chronic obstructive lung disease, benign prostate gland hypertrophy and diseases of lower urinary tract. ^ 11 cl, 30 ex, 7 tbl
申请公布号 RU2448967(C2) 申请公布日期 2012.04.27
申请号 RU20090103316 申请日期 2007.07.03
申请人 SK KEMIKALZ KO., LTD. 发明人 KIM DZAE-SUN;KIM NAM KHO;LI DZIN JOUNG;LI NAM KIU;LI JOON-DZUNG;DZANG VOO DZAE;JOUN VON-NO;OKH DZOON GIO;SUNG DZIN-KHEUNG;UM KEJ AN
分类号 A61K31/517;A61P9/12;A61P11/00;A61P13/08;A61P15/10;C07D241/04;C07D487/04 主分类号 A61K31/517
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