ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND

摘要

Provided is a compound useful as an inhibitor of the kinase activity of an EML4-ALK fusion protein or the like. The present inventors have made intensive studies on compounds useful for the treatment of cancer. Consequently, it is found that this arylaminoheterocyclic carboxamide compound has an inhibitory activity on the kinase activity of an EML4-ALK fusion protein as well as an inhibitory activity on the kinase activity of a RET fusion protein or on the kinase activity of a ROS fusion protein, and also has a good anti-tumor proliferation inhibitory activity or a good tumor regression activity. On the basis of these findings, the present invention has been accomplished. This compound can be used in a pharmaceutical composition for preventing and/or treating cancer, particularly lung cancer, non-small cell lung cancer, small cell lung cancer or the like.