发明名称 |
IN SITU FORMING HYDROGEL AND BIOMEDICAL USE THEREOF |
摘要 |
Disclosed are in situ-forming injectable hydrogel and medical uses thereof. In the in situ-forming injectable hydrogel two or more homogeneous or heterogeneous polymers are bonded to each other by a dehydrogenation reaction between phenol or aniline moieties on adjacent polymers, wherein a polymer backbone is grafted with a phenol or aniline moiety using a linker. In contrast to conventional hydrogel, the in situ-forming injectable hydrogel is superior in terms of in vivo stability and mechanical strength thanks to the introduction of a water-soluble polymer as a linker which leads to an improvement in the reactivity of phenol or aniline moieties. Having the advantage of superior bio stability and mechanical strength, the hydrogel finds a variety of applications in the biomedical field.
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申请公布号 |
US2012100103(A1) |
申请公布日期 |
2012.04.26 |
申请号 |
US201013381843 |
申请日期 |
2010.07.01 |
申请人 |
PARK KI-DONG;JOUNG YOON-KI;PARK KYUNG-MIN |
发明人 |
PARK KI-DONG;JOUNG YOON-KI;PARK KYUNG-MIN |
分类号 |
A61K38/39;A61F2/16;A61K33/24;A61K39/00;A61K39/395;A61P1/02;A61P9/00;A61P13/00;A61P17/02;A61P19/04;A61P19/08;A61P29/00;A61P31/04;A61P35/00 |
主分类号 |
A61K38/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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