发明名称 POLYNUCLEOTIDES ENCODING ANTIGENIC HIV TYPE C POLYPEPTIDES, POLYPEPTIDES AND USE THEREOF
摘要 <P>PROBLEM TO BE SOLVED: To provide polynucleotides encoding antigenic HIV type C polypeptides and polypeptides, and to provide a method for using the same. <P>SOLUTION: Uses of the polypeptides in applications including immunization, generation of packaging cell lines, and production of HIV polypeptides are also described. Polynucleotides encoding antigenic HIV polypeptides are described, as are uses of the polynucleotides and polypeptide products therefrom, including formulations of immunogenic compositions and uses thereof. In certain embodiments, the present invention relates to isolated wild-type polynucleotides and/or expression cassettes encoding HIV polypeptides, including, but not limited to, Env, Gag, Pol, Prot, RT, Int, Vpr, Vpu, Vif, Nef, Tat, Rev and/or combinations and fragments thereof. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012080895(A) 申请公布日期 2012.04.26
申请号 JP20110270228 申请日期 2011.12.09
申请人 NOVARTIS VACCINES & DIAGNOSTICS INC;UNIV OF STELLENBOSCH 发明人 ZUR MEGEDE JAN;BARNETT SUSAN W;LIAN YING;ENGELBRECHT SUSAN;VAN RENSBURG ESTRELITA JANSE;SCRIBA THOMAS JENS
分类号 C12N15/09;A61K9/127;A61K31/7088;A61K35/12;A61K35/76;A61K38/00;A61K39/00;A61K39/21;A61K47/02;A61K48/00;A61P31/18;A61P37/00;C07K14/16;C12N1/15;C12N1/19;C12N1/21;C12N5/02;C12N5/10;C12N7/00;C12N15/867;C12P21/02 主分类号 C12N15/09
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