发明名称 |
CAMKK-BETA AS A TARGET FOR TREATING CANCER |
摘要 |
Provided herein are compounds, compositions, including pharmaceutical compositions, having anti-cancer activity. Also provided are methods for diagnosing, detecting, and treating cancer in a subject, as well as a method for evaluating cancer stage in a subject, wherein the methods include determining the amount of a Ca2+/calmodulin dependent kinase kinase (CaMKK) in a sample. Further provided are methods of screening and identifying a compound that inhibits CaMKK. |
申请公布号 |
WO2012024255(A3) |
申请公布日期 |
2012.04.26 |
申请号 |
WO2011US47846 |
申请日期 |
2011.08.16 |
申请人 |
DUKE UNIVERSITY;MCDONNELL, DONALD, P.;FRIGO, DANIEL;MEANS, ANTHONY, R. |
发明人 |
MCDONNELL, DONALD, P.;FRIGO, DANIEL;MEANS, ANTHONY, R. |
分类号 |
C12N9/12;A61K31/12;C12Q1/68 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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