| 发明名称 |
ANTI-FERROPORTIN 1 MONOCLONAL ANTIBODIES AND USES THEREOF |
| 摘要 |
Provided are monoclonal antibodies and antigen-binding fragments thereof that bind to, and inhibit the activity of human FPN1, and which are effective in maintaining or increasing the transport of iron out of mammalian cells and/or maintaining or increasing the level of serum iron, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a subject in vivo.
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| 申请公布号 |
US2012100148(A9) |
申请公布日期 |
2012.04.26 |
| 申请号 |
US20090628263 |
申请日期 |
2009.12.01 |
| 申请人 |
LEUNG DONMIENNE DOEN MUN;LUAN PENG;MANETTA JOSEPH VINCENT;TANG YING;WITCHER DERRICK RYAN |
发明人 |
LEUNG DONMIENNE DOEN MUN;LUAN PENG;MANETTA JOSEPH VINCENT;TANG YING;WITCHER DERRICK RYAN |
| 分类号 |
A61K39/395;A61P7/00;A61P35/00;C07H21/00;C07K16/00;C12N5/07;C12N15/63;C12P21/08 |
主分类号 |
A61K39/395 |
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