发明名称 NOVEL SYNTHESIS OF NUCLEOSIDE 5 ' -TRIPHOSPHATES AND THEIR DERIVATIVES
摘要 Disclosed are compounds of nucleoside 5 '-triphosphates of formula (I), or derivatives thereof, or pharmaceutically acceptable salts of said nucleoside 5 '-triphosphates or said derivatives, wherein the Base of formula (I) is Adenine (A), Cytosine (C), Guanine (G), Thymine (T), Uracil (U), modified nucleobase or unnatural nucleobase; R1 is H or OH, R2 is H or OH, X is independently selected from the group consisting of O, S and Se; and Y is independently selected from the group consisting of O, B (borano, or BH3), S, and Se. Also disclosed are processes of preparing the compounds of formula (I), said process comprising steps according to Scheme A:
申请公布号 WO2012024625(A3) 申请公布日期 2012.04.26
申请号 WO2011US48485 申请日期 2011.08.19
申请人 SENA RESEARCH, INCORPORATED;HUANG, ZHEN 发明人 HUANG, ZHEN
分类号 C07H19/10;C07H19/20;C07H21/00 主分类号 C07H19/10
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