发明名称 |
METHODS FOR DETERMINING ANTI-DRUG ANTIBODY ISOTYPES |
摘要 |
The present invention provides assay methods for the determination of one or more anti-drug antibody (ADA) isotypes in a sample. As a non-limiting example, the assays of the present invention are particularly useful for determining different ADA isotypes in samples from ADA-positive patients receiving an anti-TNFa drug such as REMICADETM (infliximab) or HUMIRATM (adalimumab). The present invention also provides methods for optimizing therapy and/or reducing toxicity in subjects receiving TNFa inhibitors for the treatment of TNFa-mediated disease or disorders.
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申请公布号 |
CA2815026(A1) |
申请公布日期 |
2012.04.26 |
申请号 |
CA20112815026 |
申请日期 |
2011.10.18 |
申请人 |
NESTEC S.A. |
发明人 |
WANG, SHUI LONG;OHRMUND, LINDA;HAUENSTEIN, SCOTT;SINGH, SHARAT |
分类号 |
G01N33/558;G01N33/68 |
主分类号 |
G01N33/558 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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