发明名称 NEURAL REGENERATING CELLS WITH ALTERATIONS IN DNA METHYLATION
摘要 Disclosed herein are cells, that are descendents of marrow adherent stem cells (MASCs), capable of rescuing and/or reversing various neural disorders after transplantation into sites of central nervous system (CNS) or peripheral nervous system (PNS) injury. The cells contain alterations in the methylation state of certain genes, compared to their methylation state in MASCs. Methods of making cells capable of rescuing and/or reversing various neural disorders after transplantation into sites of CNS or PNS injury, by alteration of the methylation status of certain genes, are also provided.
申请公布号 EP2274430(A4) 申请公布日期 2012.04.25
申请号 EP20090739212 申请日期 2009.04.30
申请人 SANBIO, INC. 发明人 CASE, CASEY
分类号 C12N15/63;C12N5/0775;C12Q1/68 主分类号 C12N15/63
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