| 发明名称 |
THIAZOLOPYRIDIN-2-YLOXY-PHENYL AND THIAZOLOPYRAZIN-2-YLOXY-PHENYL AMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE |
| 摘要 |
Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity. |
| 申请公布号 |
ZA201008054(B) |
申请公布日期 |
2012.04.25 |
| 申请号 |
ZA20100008054 |
申请日期 |
2010.11.10 |
| 申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
BACANI GENESIS M;CHEUNG EUGENE Y;DENG XIAOHU;GOMEZ LAURENT;KEARNEY AARON M;LEE-DUTRA ALICE;LOCHNER SUSANNE;SANTILLAN JR ALEJANDRO;SEPASSI KIA;WICKBOLDT ALVAH T;BROGGINI DIEGO;CHROVIAN CHRISTA C;FOURIE ANNE M;GRICE CHERYL A;LANDRY-BAYLE ADRIENNE M;LIANG JIMMY T;MANI NEELAKANDHA S;SAPPEY KATHLEEN C;TANIS VIRGINIA M;WIENER JOHN J M;HARTMUT BURGHARD ZINGER |
| 分类号 |
A61K;C07D |
主分类号 |
A61K |
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