发明名称 Preparation of Phenoxyacetic Acids
摘要 1,185,208. Diuretics. MERCK & CO. Inc. 30 Oct., 1967 [2 Nov., 1966], No. 49150/67. Heading A5B. [Also in Division C2] Therapeutic compositions having diuretic and saluretic properties, in forms suitable for oral and parenteral administration, comprise, together with a suitable carrier and optionally further known diuretics and saluretics, compounds of the formula wherein R represents a hydrogen atom or an alkyl, trifluoromethyl-C 1-5 alkyl, or cycloalkyl radical, R<SP>1</SP> represents a hydroxy, C 1-5 -alkoxy, amino, C 1-5, alkylamino, group or a group of the formula-OM where M represents an alkali metal; each X, the same or different, represents a hydrogen or halogen atom or an C 1-5 alkyl, C 1-5 alkoxy or trifluoromethyl group or two X radicals or adjacent carbon atoms of the benzene ring form a bivalent hydrocarbon chain having 3 or 4 carbon atoms between its points of attachment or n represents 1, 2, 3 or 4.
申请公布号 GB1185208(A) 申请公布日期 1970.03.25
申请号 GB19670049150 申请日期 1967.10.30
申请人 MERCK & CO. INC. 发明人 EDWARD JETHRO CRAGOE, JR.
分类号 A61K31/165;A61K31/19;A61K31/215;C07C51/353;C07C51/377;C07C59/90;C07D309/22 主分类号 A61K31/165
代理机构 代理人
主权项
地址