发明名称 |
VAGINALLY ADMINISTERED ANTI-DYSRHYTHMIC AGENTS FOR TREATING PELVIC PAIN |
摘要 |
The invention relates to a pharmaceutical composition for relieving pelvic pain or infertility associated with uterine dysrhythmia. The composition includes a locally-administered anti-dysrhythmic treating agent and a bioadhesive extended-release carrier. The composition may be delivered in an extended release formulation that includes a bioadhesive, water-swellable , water-insoluble, cross-linked polycarboxylic acid polymer, such as polycarbophil. The treating agent may be a local anesthetic, such as lidocaine. The invention also relates to a method of treating or preventing pelvic pain, or treating or improving infertility, by inserting a mixture of an anti-dysrhythmic treating agent and a bioadhesive carrier into the vagina of the patient to be treated.
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申请公布号 |
CA2465132(C) |
申请公布日期 |
2012.04.24 |
申请号 |
CA20022465132 |
申请日期 |
2002.10.28 |
申请人 |
COLUMBIA LABORATORIES (BERMUDA) LIMITED |
发明人 |
LEVINE, HOWARD L.;BOLOGNA, WILLIAM J.;DE ZIEGLER, DOMINIQUE |
分类号 |
A61K47/32;A61K9/00;A61K9/20;A61K31/00;A61K31/137;A61K31/167;A61K31/192;A61K31/245;A61K31/554;A61K45/00;A61K47/10;A61K47/12;A61K47/38;A61P15/00;A61P15/02 |
主分类号 |
A61K47/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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