发明名称 Nuclease-based method for detecting and quantitating oligonucleotides
摘要 A method for quantitating an oligonucleotide in a sample of bodily fluid and/or extract is provided. The method provides for the detection and/or localization of oligonucleotides, including administered modified oligonucleotides, for therapeutic and/or pharmacokinetic purposes.
申请公布号 US8163477(B2) 申请公布日期 2012.04.24
申请号 US20030445996 申请日期 2003.05.27
申请人 YU ZHENGRONG;BAKER BRENDA F.;WU HONGJIANG;ISIS PHARMACEUTICALS, INC 发明人 YU ZHENGRONG;BAKER BRENDA F.;WU HONGJIANG
分类号 C07H21/04;C12Q1/68 主分类号 C07H21/04
代理机构 代理人
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