发明名称 |
Method of expressing long-chain prenyl diphosphate synthase |
摘要 |
The present disclosure describes a method of producing a long-chain prenyl diphosphate synthase (in particular decaprenyl diphosphate synthase and solanesyl diphosphate synthase) using a gene and a protein which are required for enabling or enhancing the activity expression of a eukaryote-derived long-chain prenyl diphosphate synthase as well as a method of efficiently producing a coenzyme Q having a long-chain isoprenoid in its side chain (in particular coenzyme Q9 or coenzyme Q10) using a microorganism. The present disclosure also describes a DNA having a base sequence shown under SEQ ID NO:1, 3 or 5 and a DNA sequence derived from the above base sequence by deletion, addition, insertion and/or substitution of one to several bases thereof, and coding for a protein enabling (functioning) or enhancing the activity expression of a eukaryote-derived long-chain prenyl diphosphate synthase in a cell of a host organism. |
申请公布号 |
US8163525(B2) |
申请公布日期 |
2012.04.24 |
申请号 |
US20080139175 |
申请日期 |
2008.06.13 |
申请人 |
MATSUDA HIDEYUKI;KAWAMUKAI MAKOTO;YAJIMA KAZUYOSHI;KANEKA CORPORATION |
发明人 |
MATSUDA HIDEYUKI;KAWAMUKAI MAKOTO;YAJIMA KAZUYOSHI |
分类号 |
C12P7/66;C12N1/21;C12N9/10 |
主分类号 |
C12P7/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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