LIPID COATED HYDROGEL AND THE PROCESS FOR PREPARING THEREOF

摘要

PURPOSE: A method for preparing lipid-coated hydrogel particles is provided to prevent reduction of sealing efficiency of a drug. CONSTITUTION: A method for preparing lipid-coated hydrogel particles comprises: a step of preparing hydrogel particles using water soluble polymers and water soluble crosslinking agent; a step of dissolving the lipid in organic solvent; a step of dispersing the hydrogel particles to the organic solvent; and a step of adding water to the dispersed liquid and performing reduced pressure distillation. The organic solvent is main organic solvent or alcohol of C1-C6.