摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to pharmaceutics, and concerns a dosage form presented in the form of a capsule having a shell wall, a linker or another capsule subunit consisting of a pharmaceutically acceptable composition containing (i) ammonium methacrylate copolymer type A (Eudragit RL), (ii) at least one excipient modifying dissolution and presenting a hydroxypropyl cellulose polymer blend of various molecular weights and (iii) a lubricating agent. ^ EFFECT: invention provides polymer compositions applicable for melt extrusion and injection moulding, enabling time variations of shell dissolution and components release from the capsule. ^ 32 cl, 12 ex |