发明名称 |
A MEDICINAL FUSIDIC ACID CREAM MADE USING SODIUM FUSIDATE AND INCORPORATING A BIOPOLYMER AND A PROCESS TO MAKE IT |
摘要 |
<p>The present invention is directed to a medicinal composition for treating bacterial skin infections and related wounds, and also other skin wounds including those caused by burns. The cream also causes skin rejuvenation through an epithelisation process. The cream comprises a) a biopolymer in the form of Chitosan, b) an Active Pharmaceutical Ingredient (API), in the form of fusidic, c) a cream base, and d) water. The invention also discloses a process to make the medicinal cream in which Fusidic acid which is formed in situ from Sodium Fusidate as the starting raw material, by converting it into Fusidic acid under oxygen-free environment created using inert gas, preferably nitrogen. The cream produced by the process of the present invention has greater shelf-life stability and the finer particle size of the API than the conventional creams containing Fusidic acid and found to be surprisingly superior for use against skin infections with allergy & itching, & wounds on human skin than alternative creams currently available.</p> |
申请公布号 |
WO2012049545(A1) |
申请公布日期 |
2012.04.19 |
申请号 |
WO2010IB56134 |
申请日期 |
2010.12.30 |
申请人 |
VANANGAMUDI, SULUR, SUBRAMANIAM;SRINIVASAN, MADHAVAN;CHULLIEL, NEELAKANDAN, NARAYANAN;SENTHILKUMAR, KUPPUSAMY |
发明人 |
VANANGAMUDI, SULUR, SUBRAMANIAM;SRINIVASAN, MADHAVAN;CHULLIEL, NEELAKANDAN, NARAYANAN;SENTHILKUMAR, KUPPUSAMY |
分类号 |
A61K9/00;A61K9/107;A61K31/00;A61K47/10;A61K47/36 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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