PERMISSIVE CELL LINE TO THE PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS

摘要

The present invention relates to a permissive cell line to the porcine reproductive and respiratory syndrome (PRRS) virus, which expresses the tailless pCD163 polypeptide. The permissive cell line to the porcine reproductive and respiratory syndrome virus of the present invention is highly infectious to the PRRS virus, and thus improves the proliferation rate of the PRRS virus through tailless pCD163 expression with porcine cytoplasmic domain defects. Therefore, the cell line of the present invention may yield porcine reproductive and respiratory syndrome viruses with high efficiency. The thus-obtained PRRS viruses can be effectively used in vaccines for preventing porcine reproductive and respiratory syndrome.