发明名称 SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION
摘要 The purpose of the present invention is to provide a pharmaceutical composition which comprises a medicinal agent and a collagen and has good handleability and sustained release properties. The purpose is achieved by a sustained-release pharmaceutical composition comprising a medicinal agent, a collagen and at least one saccharide selected from monosaccharides, disaccharides, trisaccharides and tetrasaccharides. The present inventors have found that a collagen containing a saccharide is gelated when the collagen is administered to a living body. Based on this finding, it is also found that the release rate of a medicinal agent can be controlled when the medicinal agent is prepared into a composition comprising the medicinal agent, a collagen and a saccharide, and that the composition can be used as a sustained-release pharmaceutical composition.
申请公布号 WO2012050184(A1) 申请公布日期 2012.04.19
申请号 WO2011JP73632 申请日期 2011.10.14
申请人 KYOTO UNIVERSITY;KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION;KAKEN PHARMACEUTICAL CO., LTD.;KOKEN CO., LTD.;FUKUSHIMA, MASANORI;MASTUBARA, HIROAKI;MATOBA, SATOAKI;HIJIKATA, SHIGEKI;ASO, YU;SATO, TSUTOMU 发明人 FUKUSHIMA, MASANORI;MASTUBARA, HIROAKI;MATOBA, SATOAKI;HIJIKATA, SHIGEKI;ASO, YU;SATO, TSUTOMU
分类号 A61K47/42;A61K9/08;A61K38/00;A61K38/27;A61K45/00;A61K47/26;A61K47/36;A61P1/02;A61P9/00;A61P9/10;A61P17/02;A61P19/00;A61P35/00;A61P43/00 主分类号 A61K47/42
代理机构 代理人
主权项
地址