发明名称 |
METHOD FOR DETERMINING COPY NUMBER VARIATIONS |
摘要 |
The invention provides a method for determining copy number variations (CNV) of a sequence of interest in a test sample that comprises a mixture of nucleic acids that are known or are suspected to differ in the amount of one or more sequence of interest. The method comprises a statistical approach that accounts for accrued variability stemming from process-related, interchromosomal and inter-sequencing variability. The method is applicable to determining CNV of any fetal aneuploidy, and CNVs known or suspected to be associated with a variety of medical conditions.
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申请公布号 |
US2012094849(A1) |
申请公布日期 |
2012.04.19 |
申请号 |
US201113333832 |
申请日期 |
2011.12.21 |
申请人 |
RAVA RICHARD P.;RHEES BRIAN KENT;VERINATA HEALTH, INC. |
发明人 |
RAVA RICHARD P.;RHEES BRIAN KENT |
分类号 |
C12Q1/68;C40B20/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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地址 |
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