| 发明名称 |
Compositions and methods of using chondroitinase ABCI mutants |
| 摘要 |
One aspect of the present invention relates to mutants of chondroitinase ABCI. Such chondroitinase ABCI mutants exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including exposure to UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided. |
| 申请公布号 |
AU2006294755(B2) |
申请公布日期 |
2012.04.19 |
| 申请号 |
AU20060294755 |
申请日期 |
2006.09.26 |
| 申请人 |
ACORDA THERAPEUTICS, INC. |
发明人 |
IACI, JENNIFER;VECCHIONE, ANDREA;MARKENSOHN, ELIZABETH;CAGGIANO, ANTHONY O. |
| 分类号 |
C12N9/00;C07H21/04;C12N1/20;C12N9/88;C12N15/00 |
主分类号 |
C12N9/00 |
| 代理机构 |
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| 主权项 |
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