发明名称 |
MODIFIED ERYTHROPOIETIN (EPO) POLYPEPTIDES THAT EXHIBIT INCREASED PROTEASE RESISTANCE AND PHARMACEUTICAL COMPOSITIONS THEREOF |
摘要 |
Modified erythropoietin (EPO) polypeptides and other modified therapeutic polypeptides are provided. The EPO polypeptides and other therapeutic polypeptides are modified to exhibit physical properties and activities that differ from the unmodified EPO polypeptides and other unmodified therapeutic polypeptides, respectively. Nucleic acid molecules encoding these polypeptides also are provided. Also provided are methods of treatment and diagnosis using the polypeptides. |
申请公布号 |
US2012094906(A1) |
申请公布日期 |
2012.04.19 |
申请号 |
US20090736959 |
申请日期 |
2009.05.29 |
申请人 |
GUYON THIERRY;BORRELLY GILLES;GALLET XAVIER;DRITTANTI LILA;VEGA MANUEL;HANALL BIOPHARMA CO. LTD |
发明人 |
GUYON THIERRY;BORRELLY GILLES;GALLET XAVIER;DRITTANTI LILA;VEGA MANUEL |
分类号 |
A61K38/18;A61P7/06;C07K14/505;C12N1/13;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12N15/63 |
主分类号 |
A61K38/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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