发明名称 |
DETECTING AND TREATING BREAST CANCER RESISTANCE TO EGFR INHIBITORS |
摘要 |
The application describes therapeutic compositions and methods for treating cancer. For example, therapeutic compositions and methods related to inhibition of FAM83A (family with sequence similarity 83) are provided. The application also describes methods for diagnosing cancer resistance to EGFR inhibitors. For example, a method of diagnosing cancer resistance to EGFR inhibitors by detecting increased FAM83A levels is described. |
申请公布号 |
US2012094843(A1) |
申请公布日期 |
2012.04.19 |
申请号 |
US201113248690 |
申请日期 |
2011.09.29 |
申请人 |
MEIER ROLAND;MOONLEE SUN-YOUNG;KENNY PARAIC A.;BISSELL MINA J.;FURUTA SAORI;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MEIER ROLAND;MOONLEE SUN-YOUNG;KENNY PARAIC A.;BISSELL MINA J.;FURUTA SAORI |
分类号 |
C40B30/06;C12Q1/02;C40B20/00;G01N21/64;G01N33/566 |
主分类号 |
C40B30/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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