The present invention relates to viscosity stabilized ophthalmic formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a diol alcohol such as sorbitol and, optionally, a pharmaceutically acceptable divalent cation salt such as magnesium chloride.
申请公布号
WO2011140203(A3)
申请公布日期
2012.04.19
申请号
WO2011US35165
申请日期
2011.05.04
申请人
ALCON RESEARCH, LTD.;KETELSON, HOWARD, ALLEN;DAVIS, JAMES, W.;MEADOWS, DAVID, L.
发明人
KETELSON, HOWARD, ALLEN;DAVIS, JAMES, W.;MEADOWS, DAVID, L.