| 摘要 |
<p>(A) Cpds. (I) R=(1-4C) alkyl or Ph, R1=(1-4C) alkyl Ac=(2-4C) aliphatic acyl A=(2-4C) alkylene. (B) Metal and amine salts of (I) (C) Esters of (I). X-ray contrast agents, esp. for oral cholecystotraphy. I (R1=Et, Ac=MeCO, A=CH2CH2, R=Me) has LD50=1380 mg/kg (p.o). Administration of 100 mg/kg in rabbit, gave, after 3 hr., 24.2 mg/kg, in the gall-bladder and 10.93 mg/kg in the urine. Adult dose - ca 3 g.</p> |
