发明名称 |
PHARMACEUTICAL DOSAGE FORM FOR ORAL ADMINISTRATION OF A BCL-2 FAMILY INHIBITOR |
摘要 |
The invention relates to a pharmaceutical dosage form which comprises a solid dispersion product comprising N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1-((phenylsulfanyl)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide or a salt, hydrate or solvate thereof, at least one pharmaceutically acceptable polymer, and at least one pharmaceutically acceptable solubilizer. The invention is further directed to processes for preparing the pharmaceutical dosage form and to use of the dosage form for treating proliferative disorders. |
申请公布号 |
EP2440177(A2) |
申请公布日期 |
2012.04.18 |
申请号 |
EP20100742875 |
申请日期 |
2010.06.08 |
申请人 |
ABBOTT GMBH & CO. KG |
发明人 |
PACKHAEUSER, CLAUDIA;STEIGER, NORBERT;LIEPOLD, BERND;KOSTELAC, DRAZEN;KNOBLOCH, MARTIN |
分类号 |
A61K9/00;A61K9/14;A61K31/5377 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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