Polymorphic forms α, &bgr; and γ of rifaximin

摘要

Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin &bgr;, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.