发明名称 |
Methods of generating protein variants |
摘要 |
The present invention provides methods of designing and generating polypeptide variants that have altered properties compared to a parent polypeptide. The present invention further provides a computer program product for carrying out the design of a variant polypeptide. The present invention further provides nucleic acids encoding enzyme variants, as well as vectors and host cells comprising the nucleic acids. The present invention further provides variant enzymes; methods of producing the variant enzymes; and methods of producing compounds using the enzymes. |
申请公布号 |
US8158383(B2) |
申请公布日期 |
2012.04.17 |
申请号 |
US20080049008 |
申请日期 |
2008.03.14 |
申请人 |
KEASLING JAY D.;YOSHIKUNI YASUO;DIETRICH JEFFREY ALLEN;NOWROOZI FARNAZ F.;BABBITT PATRICIA C.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
KEASLING JAY D.;YOSHIKUNI YASUO;DIETRICH JEFFREY ALLEN;NOWROOZI FARNAZ F.;BABBITT PATRICIA C. |
分类号 |
C12P21/06;C07H21/02;C07K14/00 |
主分类号 |
C12P21/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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