METHOD FOR TREATING PARKINSON'S DISEASE THROUGH THE CONTROL OF THE VDAC1 PROTEIN

摘要

The present invention relates to a method for treating Parkinson's disease through the control of the voltage-dependent anion channel 1 (VDAC1) protein. In particular, the present invention relates to a pharmaceutical composition for treating Parkinson's disease including a VDAC1 protein controller. The VDAC1 protein controller comprises: a drug that inhibits the generation of the mRNA of VDAC1, a drug that inhibits mitochondrial permeability transition pore (MPTP), a mitochondrial calcium uptake inhibitor, etc. The present invention also relates to a method for treating Parkinson's disease comprising the step of dosing an individual with a VDAC1 protein controller. The present invention is expected to be capable of providing a method for fundamentally treating Parkinson's disease by preventing abnormal mitochondrial function and/or restoring same.