| 发明名称 |
METHOD FOR THE TREATMENT OF ACUTE MYELOID LEUKEMIA |
| 摘要 |
The invention is in the field of molecular medicine and provides methods for the treatment of acute myeloid leukemia. These methods are based on the observation that microRNA-9 and microRNA-9* are involved in the pathogenesis of the disease in that the overexpression of microRNA-9/9* block myeloid differentiation in vitro. More in particular, microRNA-9/9* were found to play a role in leukemic transformation in acute myeloid leukemia. |
| 申请公布号 |
US2012088811(A1) |
申请公布日期 |
2012.04.12 |
| 申请号 |
US201013138914 |
申请日期 |
2010.04.22 |
| 申请人 |
LOEWENBERG BOB;JONGEN-LAVRENCIC MOJCA;VALK PETER JACOBUS MARIA;SUN SU MING;ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM |
发明人 |
LOEWENBERG BOB;JONGEN-LAVRENCIC MOJCA;VALK PETER JACOBUS MARIA;SUN SU MING |
| 分类号 |
A61K31/7088;A61P35/02;C07H21/02 |
主分类号 |
A61K31/7088 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
