| 发明名称 |
ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 24P4C12 PROTEINS |
| 摘要 |
Antibody drug conjugates (ADC's) that bind to 24P4C12 protein and variants thereof are described herein. 24P4C12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer. |
| 申请公布号 |
KR20120034591(A) |
申请公布日期 |
2012.04.12 |
| 申请号 |
KR20117023550 |
申请日期 |
2010.03.05 |
| 申请人 |
AGENSYS, INC.;SEATTLE GENETICS, INC. |
发明人 |
GUDAS JEAN;JAKOBOVITS AYA;AN ZILI;MORRISON ROBERT KENDALL;MORRISON KAREN JANE MEYRICK;JIA XIAO CHI;BENJAMIN DENNIS;MOSER RUTH;SENTER PETER |
| 分类号 |
A61K39/395;C12P21/08 |
主分类号 |
A61K39/395 |
| 代理机构 |
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