发明名称 |
COMPOSITION FOR SUPPRESSING TISSUE INJURY CAUSED BY AUTOIMMUNE DISEASE AND USE THEREOF |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a composition for suppressing tissue injury caused by autoimmune diseases by clarifying the mechanism of cross-presentation of dendritic cells and a gene and a protein controlling the cross-presentation and using the clarified facts, and to provide a technology to use the composition. <P>SOLUTION: The composition for suppressing tissue injury caused by autoimmune diseases includes, as an active component, an agent to inhibit release of an antigen substance from an endosome of a dendritic cell to cytoplasm. <P>COPYRIGHT: (C)2012,JPO&INPIT |
申请公布号 |
JP2012072135(A) |
申请公布日期 |
2012.04.12 |
申请号 |
JP20110192115 |
申请日期 |
2011.09.02 |
申请人 |
INSTITUTE FOR RHEUMATIC DISEASES CO LTD |
发明人 |
TSUMIYAMA MASARU;TAKIMOTO MAI;SHIOZAWA SHUNICHI |
分类号 |
A61K45/00;A01K67/027;A61K38/00;A61P1/00;A61P1/16;A61P3/10;A61P7/06;A61P17/00;A61P19/02;A61P37/00;C07K14/21;C07K14/47;C12N15/113;C12Q1/02;G01N33/15;G01N33/50 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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