发明名称 |
PHARMACEUTICAL COMPOSITIONS COMPRISING GLIMEPIRIDE AND POLYETHYLENE GLYCOL CASTOR OIL |
摘要 |
<p>The present invention relates to the field of a pharmaceutical technology. More specifically, the present invention relates to a pharmaceutical composition comprising glimepiride and a surface active agent. Surface active agent obtainable by reacting castor oil or hydrogenated castor oil with ethylene oxide, preferably hydrogenated castor oil, substantially improves dissolution glimepiride active pharmaceutical ingredient and at the same time, when both formulated into a pharmaceutical composition, ensures satisfying or exceeding other parameters like for example stability, hardness, friability and handling of said pharmaceutical composition.</p> |
申请公布号 |
WO2012045863(A1) |
申请公布日期 |
2012.04.12 |
申请号 |
WO2011EP67552 |
申请日期 |
2011.10.07 |
申请人 |
LEK PHARMACEUTICALS D.D.;JAKLIC, MIHA TOMAZ;REVEN, SEBASTJAN |
发明人 |
JAKLIC, MIHA TOMAZ;REVEN, SEBASTJAN |
分类号 |
A61K9/20;A61K9/16;A61K31/4439;A61K31/64 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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