MIRNA AND MIRNA INHIBITORS THAT MODULATE ADENOVIRUS REPLICATION AND/OR ADENOVIRUS INDUCED CELL DEATH

摘要

The invention relates to means and methods for identifying a mi RNA, a mi RNA mimic or a mi RNA inhibitor that modulates adenovirus replication in, and/or adenovirus induced cell death of a cell. Identified mi RNAs, mi RNA mimics or mi RNA inhibitors are used as anti-cancer agents in the context of adenovirus gene therapy.