| 摘要 |
PURPOSE: A synthesizing method of aromatic bromides or aromatic chlorides is provided to have very simple and mild reaction condition, and to successfully synthesize aromatic bromides or aromatic chlorides from aromatic amine compounds with various substituents by using copper salt of catalytic amount. CONSTITUTION: A synthesizing method of aromatic bromides or aromatic chlorides in chemical formula 2: Ar-X from aromatic amine comprises: a step of adding sodium nitrite, alkyl nitride, p-TsOH, and ionic halogenide into aromatic an amine compound in chemical formula 1: Ar-HN2; a step of adding minimum amount of water not using organic solvent. And the ionic halogenide is selected from a group consisting of sodium bromide, potassium bromide, tetrabutyl ammonium bromide, and bezyltriethyl ammonium chloride.
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