METHODS OF MODULATING FUCOSYLATION OF GLYCOPROTEINS
摘要
The present invention provides methods and materials useful for monitoring and regulating the glycosylation of glycoproteins that are recombinantly produced from cells. In particular, methods are provided for monitoring and regulating levels of cellular indicators which affect the level of fucosylation produced by cells.
申请公布号
EP2438185(A1)
申请公布日期
2012.04.11
申请号
EP20100784174
申请日期
2010.06.04
申请人
MOMENTA PHARMACEUTICALS, INC.
发明人
COLLINS, BRIAN, EDWARD;THIRUNEELAKANTAPILLAI, LAKSHMANAN;BULIK, DOROTA, A.;MILLEA, KEVIN