A compound of formula (I) Or its salts or pharmaceutically acceptable derivatives thereof wherein; A represents a chemical moiety with the general formula (II): X is selected from a group consisting of CH2, C(═O), CH(R5), C(R5)(R6) or C(R5)(R6)CH2; R1 is selected from the group consisting of optionally substituted arylalkyl, and optionally substituted heteroarylalkyl; R2 is selected from the group consisting of optionally substituted aryl or optionally substituted heteroaryl or NR7R8; R3 R4 R5 R6 R7 and R8 are as defined herein; and n=1 or 2 is provided. Pharmaceutical compositions comprising the compounds are also provided. The compounds are useful in treating various conditions including arrhythmia.
申请公布号
EP2438044(A1)
申请公布日期
2012.04.11
申请号
EP20100722754
申请日期
2010.06.04
申请人
XENTION LIMITED
发明人
HAMLYN, RICHARD, JOHN;MADGE, DAVID;MULLA, MUSHTAQ;JONES, SIMON, MARK;HARTZOULAKIS, BASIL;JOHN, DEREK, EDWARD