PHARMACEUTICAL FORMS WITH IMPROVED PHARMACOKINETIC PROPERTIES

摘要

Formulation (I) that disintegrates quickly in the mouth, comprises vardenafil, where at least 80% of the vardenafil dose dissolves at 25[deg]C in 10 ml of physiological saline and the release rate of (I) in 900 ml of physiological saline is at least 70% within the first 5 minutes in the USP (titanium dioxide) sheet agitator device at 50 revolutions per minute at 37[deg]C. - ACTIVITY : None given. - MECHANISM OF ACTION : Cyclic guanosine monophosphate phosphodiesterase inhibitor. No biological data given.