PROCESS FOR THE PREPARATION OF AMORPHOUS RALTEGRAVIR POTASSIUM

摘要

The present invention provides novel polymorphs of raltegravir potassium, processes for their preparation and pharmaceutical compositions comprising them. Thus for example, raltegravir potassium was added to water and stirred for 15 minutes, the solution was filtered on hiflo bed and the bed washed with water, the resulting solution was subjected to freeze drying at−180 deg C. for 13 hours to give raltegravir potassium amorphous form.