| 发明名称 |
COMPOSITIONS AND METHODS FOR IMPROVED GLYCOPROTEIN SIALYLATION |
| 摘要 |
<p>The present invention provides compositions and methods for the production of glycoproteins with enhanced sialylation. In particular, the invention provides cell lines comprising disrupted sialidase expression and methods of using the cell lines to produce glycoproteins with enhanced sialylation.</p> |
| 申请公布号 |
EP2195444(A4) |
申请公布日期 |
2012.04.11 |
| 申请号 |
EP20080838267 |
申请日期 |
2008.10.13 |
| 申请人 |
SIGMA-ALDRICH CO. LLC |
发明人 |
ZHANG, MIN;ROSS, JAMES S. |
| 分类号 |
C12P21/04;C12N15/113;C12P21/06 |
主分类号 |
C12P21/04 |
| 代理机构 |
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