| 摘要 |
FIELD: medicine. ^ SUBSTANCE: group of inventions refers to medicine and concerns a recombinant bluetongue vaccine. Substance of the invention involves versions of an immunogenic composition for inducing an immune response on Orbivirus, more specifically a bluetongue virus (BTV) in an animal susceptible to BTV infection The composition may contain a pharmaceutically or veterinary acceptable binding agent or an excipient and a vector. The vector may contain a heterologous model (s) of nucleic acid expressing in vivo BTV antigen, immunogen or their VP2 and VP5 protein epitope in an animal's body. The composition may contain an adjuvant such as carbomer. Besides, the invention involves a method for inducing an immunological or protective response, and a kit. ^ EFFECT: enhanced immune response. ^ 29 cl, 19 ex, 3 tbl, 20 dwg |
