COMPOSITIONS AND METHODS FOR TREATING EPITHELIAL AND RETINAL TISSUE DISEASES
摘要
The present invention relates to mononucleoside phosphate compoundsthat have the benefits of a dinucleotide pharmaceutical. These mononucleoside phosphates can be made from a mononucleotide that has been modified byattaching a degradation resistant substituent on the terminal phosphate of apolyphosphate mononucleotide. By attaching this degradation resistant substituent, the stability from degradation matches or exceeds those of certain dinucleotides. (see formula I)
申请公布号
CA2477241(C)
申请公布日期
2012.04.10
申请号
CA20032477241
申请日期
2003.02.27
申请人
INSPIRE PHARMACEUTICALS, INC.
发明人
YERXA, BENJAMIN R.;DOUGLASS, JAMES G., III;SHAVER, SAMMY RAY;PETERSON, WARD M.;BROWN, EDWARD G.;CREAN, CHRISTOPHER S.
