发明名称 |
METHOD FOR MEASURING ACTIVITY OF PROTEOLYTIC ENZYMES OF VARIOUS TYPES OF ACTIVE CENTRES ABLE TO SPLIT IMMUNOGLOBULINS IgA, IgM, IgG |
摘要 |
FIELD: medicine. ^ SUBSTANCE: method involves tray coating with a bacterial antigen of any representative of an opportunistic microflora, coating of a sorbed antigen with IgG, IgM and IgA antibodies, a proteolytic reaction by incubation in tray wells of an analysed biological fluid together with inhibitors of active centres of the enzymes (serine, cysteine, metal-dependent), washing of the reaction products and calculation of enzymatic activity with appropriate type of the active centre. ^ EFFECT: invention provides simultaneous measurement of activity of proteinase of various origin and of various types of the active centres. ^ 4 tbl, 4 ex |
申请公布号 |
RU2447446(C2) |
申请公布日期 |
2012.04.10 |
申请号 |
RU20100127036 |
申请日期 |
2010.07.01 |
申请人 |
GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE DOPOLNITEL'NOGO PROFESSIONAL'NOGO OBRAZOVANIJA "KAZANSKAJA GOSUDARSTVENNAJA MEDITSINSKAJA AKADEMIJA FEDERAL'NOGO AGENTSTVA PO ZDRAVOOKHRANENIJU I SOTSIAL'NOMU RAZVITIJU" |
发明人 |
ZINKEVICH OLEG DANILOVICH;SAFINA NEHLLJA AKHMETOVNA;BARYSHEVA NATALIJA OLEGOVNA |
分类号 |
C12N9/50;G01N33/53;G01N33/573 |
主分类号 |
C12N9/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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