发明名称 |
NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF |
摘要 |
Provided is a method for economically and efficiently producing an optically active amino compound, which is useful as an intermediate for drugs, pesticides and so on, from a ketone compound. A novel polypeptide having a transaminase activity, said polypeptide showing a higher activity for glutamic acid than for L-alanine as an amino donor and forming (S)1-benzyl-3-pyrrolidinone at a high optical purity of 93% or greater, a gene encoding the polypeptide, and a transformant highly expressing the gene. |
申请公布号 |
WO2012043653(A1) |
申请公布日期 |
2012.04.05 |
申请号 |
WO2011JP72237 |
申请日期 |
2011.09.28 |
申请人 |
KANEKA CORPORATION;ITO NORIYUKI;NISHI AKIKO;KAWANO SHIGERU;YASOHARA YOSHIHIKO |
发明人 |
ITO NORIYUKI;NISHI AKIKO;KAWANO SHIGERU;YASOHARA YOSHIHIKO |
分类号 |
C12N15/09;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/10;C12P41/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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