| 摘要 |
<p>Disclosed are compounds of the formula (I): wherein R1, R2, X, Y, and Z as described herein, or pharmaceutically acceptable salts thereof, for use in treating or preventing neurodegenerative diseases and disorders such as Huntington's disease. Also disclosed are pharmaceutical compositions comprising such compounds or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier and methods of treating or preventing neurodegenerative diseases and disorders.</p> |
| 申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;MARUGAN, JUAN, J.;ZHENG, WEI;SOUTHALL, NOEL;HUANG, WENWEI;MCCOY, JOSHUA, G.;TITUS, STEVEN;PATNAIK, SAMARJIT |
发明人 |
MARUGAN, JUAN, J.;ZHENG, WEI;SOUTHALL, NOEL;HUANG, WENWEI;MCCOY, JOSHUA, G.;TITUS, STEVEN;PATNAIK, SAMARJIT |
