| 发明名称 |
CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF |
| 摘要 |
The present invention features compounds of formula I or pharmaceutically acceptable salts, solvates or prodrugs thereof, and methods of using the same to inhibit the metabolizing activities of CYP enzymes. The present invention also features methods of using these compounds, salts, solvates or prodrugs to improve the pharmacokinetics of drugs that are metabolized by CYP enzymes.
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| 申请公布号 |
US2012083490(A1) |
申请公布日期 |
2012.04.05 |
| 申请号 |
US201113315137 |
申请日期 |
2011.12.08 |
| 申请人 |
KLEIN LARRY L.;CHEN HUI-JU;YEUNG MING C.;FLENTGE CHARLES A.;RANDOLPH JOHN T.;HUANG PEGGY P.;HUTCHINSON DOUGLAS K.;KEMPF DALE J.;ABBOTT LABORATORIES |
发明人 |
KLEIN LARRY L.;CHEN HUI-JU;YEUNG MING C.;FLENTGE CHARLES A.;RANDOLPH JOHN T.;HUANG PEGGY P.;HUTCHINSON DOUGLAS K.;KEMPF DALE J. |
| 分类号 |
A61K31/5355;A61K31/426;A61K31/427;A61K31/4439;A61K31/4535;A61K31/496;A61K31/513;A61K31/5377;A61P31/12;A61P31/14;A61P43/00;C07D277/30;C07D417/12;C07D417/14;C12N9/99 |
主分类号 |
A61K31/5355 |
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