发明名称 |
NOVEL USE OF CRYPTOTANSHINONE |
摘要 |
The present invention relates to a composition comprising cryptotanshinone for promoting the differentiation of mesenchymal stem cells into osteoblasts, and to an osteogenesis promoter comprising cryptotanshinone and mesenchymal stem cells. According to the present invention, the differentiation of the mesenchymal stem cells into osteoblasts is promoted when the mesenchymal stem cells are treated with cryptotanshinone. The thus-differentiated mesenchymal stem cells may be directly transplanted to a patient so as to promote osteogenesis in the patient. Therefore, the composition or the osteogenesis promoter of the present invention may be used for treating a patient having impairments requiring osteogenesis promotion, such as osteoporosis, bone fractures, bone grafts including alveolar bone grafts for dental implants, and other bone defects. |
申请公布号 |
WO2012044139(A2) |
申请公布日期 |
2012.04.05 |
申请号 |
WO2011KR07324 |
申请日期 |
2011.10.04 |
申请人 |
CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATIONFOUNDATION;SHIN, JIN HEE;KIM, KYUNG SOO;LEE, IL KYU |
发明人 |
SHIN, JIN HEE;KIM, KYUNG SOO;LEE, IL KYU |
分类号 |
C12N5/0775;A61K31/343;A61P19/10;C12N5/02 |
主分类号 |
C12N5/0775 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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